Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
guaDGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (425 aa)    
Predicted Functional Partners:
pucD_1
Putative xanthine dehydrogenase subunit D.
 
 
 0.943
mop
Aldehyde oxidoreductase.
 
 
 0.943
punA
Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.930
ndhF
Nicotinate dehydrogenase FAD-subunit.
 
 
 0.924
pucD_2
Putative xanthine dehydrogenase subunit D.
 
 
 0.902
deoD_2
Purine nucleoside phosphorylase DeoD-type.
     
 0.902
preA_2
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA.
  
 
 0.878
ndhS
Nicotinate dehydrogenase small FeS subunit.
 
 
 0.865
preA_1
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA.
 
 
 0.853
hpt_2
Hypoxanthine phosphoribosyltransferase.
 
  
 0.848
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.