Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ytrA_2HTH-type transcriptional repressor YtrA. (125 aa)    
Predicted Functional Partners:
ytrB_1
ABC transporter ATP-binding protein YtrB.
 
  
 0.934
ytrA_1
HTH-type transcriptional repressor YtrA.
  
     0.743
OPJ63146.1
Hypothetical protein.
  
  
 0.671
OPJ61003.1
Hypothetical protein.
       0.570
ytrB_2
ABC transporter ATP-binding protein YtrB.
 
  
 0.510
skfE
SkfA peptide export ATP-binding protein SkfE.
 
  
 0.444
tcyP
L-cystine uptake protein TcyP; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.434
cobB_1
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
    0.425
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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