| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | guaB_1 | CLCHR_34570 | CLCHR_15930 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.576 |
| apt | guaB_3 | CLCHR_34570 | CLCHR_42470 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase. | 0.889 |
| apt | mtcA1 | CLCHR_34570 | CLCHR_27240 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Beta-carbonic anhydrase 1. | 0.624 |
| apt | purR | CLCHR_34570 | CLCHR_09950 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Pur operon repressor. | 0.773 |
| apt | xpt | CLCHR_34570 | CLCHR_21190 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.447 |
| dapH_1 | mtcA1 | CLCHR_08750 | CLCHR_27240 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. | Beta-carbonic anhydrase 1. | 0.946 |
| dauA | mtcA1 | CLCHR_05460 | CLCHR_27240 | C4-dicarboxylic acid transporter DauA. | Beta-carbonic anhydrase 1. | 0.759 |
| epsM | mtcA1 | CLCHR_48240 | CLCHR_27240 | Putative acetyltransferase EpsM. | Beta-carbonic anhydrase 1. | 0.889 |
| focA | mtcA1 | CLCHR_01260 | CLCHR_27240 | Putative formate transporter 1. | Beta-carbonic anhydrase 1. | 0.765 |
| guaB_1 | apt | CLCHR_15930 | CLCHR_34570 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.576 |
| guaB_1 | guaB_3 | CLCHR_15930 | CLCHR_42470 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Inosine-5'-monophosphate dehydrogenase. | 0.622 |
| guaB_1 | mtcA1 | CLCHR_15930 | CLCHR_27240 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Beta-carbonic anhydrase 1. | 0.602 |
| guaB_1 | purR | CLCHR_15930 | CLCHR_09950 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pur operon repressor. | 0.527 |
| guaB_1 | xpt | CLCHR_15930 | CLCHR_21190 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.858 |
| guaB_3 | apt | CLCHR_42470 | CLCHR_34570 | Inosine-5'-monophosphate dehydrogenase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.889 |
| guaB_3 | guaB_1 | CLCHR_42470 | CLCHR_15930 | Inosine-5'-monophosphate dehydrogenase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.622 |
| guaB_3 | mtcA1 | CLCHR_42470 | CLCHR_27240 | Inosine-5'-monophosphate dehydrogenase. | Beta-carbonic anhydrase 1. | 0.674 |
| guaB_3 | purR | CLCHR_42470 | CLCHR_09950 | Inosine-5'-monophosphate dehydrogenase. | Pur operon repressor. | 0.877 |
| guaB_3 | xpt | CLCHR_42470 | CLCHR_21190 | Inosine-5'-monophosphate dehydrogenase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.910 |
| mtcA1 | apt | CLCHR_27240 | CLCHR_34570 | Beta-carbonic anhydrase 1. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.624 |