Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pncB2Nicotinate phosphoribosyltransferase pncB2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (494 aa)    
Predicted Functional Partners:
nadC_1
Putative nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
   
 0.954
cinA_2
Putative competence-damage inducible protein; Belongs to the CinA family.
  
 
 0.932
nadC_2
Putative nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
   
 0.918
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.899
OPJ57963.1
Isochorismatase family protein.
 
 
 0.878
deoD_2
Purine nucleoside phosphorylase DeoD-type.
     
 0.867
nadE_1
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.858
nadB
L-aspartate oxidase.
     
 0.842
nudC_1
NADH pyrophosphatase.
    
 0.833
yfkN
Trifunctional nucleotide phosphoesterase protein YfkN precursor.
  
 
 0.831
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
Server load: low (20%) [HD]