Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uxuA_3Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (372 aa)    
Predicted Functional Partners:
mtlK
Mannitol 2-dehydrogenase.
 
 
 0.964
por
polyol:NADP oxidoreductase.
 
 
 0.929
uxaC_1
Uronate isomerase.
 
  
 0.878
uxaC_3
Uronate isomerase.
 
  
 0.877
uxaC_2
Uronate isomerase.
 
  
 0.875
uxaA
Altronate dehydratase.
 
 
 0.839
OPJ62507.1
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.789
kdgK_3
2-dehydro-3-deoxygluconokinase.
 
  
 0.785
kduD
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase.
  
 
 0.771
rpe
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.754
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
Server load: low (32%) [HD]