Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
liaRTranscriptional regulatory protein LiaR. (206 aa)    
Predicted Functional Partners:
desK
Sensor histidine kinase DesK.
 
 0.997
barA_2
Signal transduction histidine-protein kinase BarA.
  
 0.980
luxQ_2
Autoinducer 2 sensor kinase/phosphatase LuxQ.
  
 0.957
luxQ_3
Autoinducer 2 sensor kinase/phosphatase LuxQ.
  
 0.957
rpfC_1
Sensory/regulatory protein RpfC.
  
 0.957
cph2_3
Phytochrome-like protein cph2.
  
 0.953
phoR_5
Alkaline phosphatase synthesis sensor protein PhoR.
  
 0.946
frzE
Gliding motility regulatory protein.
  
 0.943
rpfC_2
Sensory/regulatory protein RpfC.
  
 0.926
cph2_2
Phytochrome-like protein cph2.
 
 0.919
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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