Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aesAcetyl esterase. (324 aa)    
Predicted Functional Partners:
hndA
NADP-reducing hydrogenase subunit HndA.
    
  0.810
hndC
NADP-reducing hydrogenase subunit HndC.
    
  0.783
hndD_3
NADP-reducing hydrogenase subunit HndC.
    
  0.783
lcfB
long-chain-fatty-acid--CoA ligase.
  
 0.752
puuB_1
Gamma-glutamylputrescine oxidoreductase.
  
 
 0.740
puuB_2
Gamma-glutamylputrescine oxidoreductase.
  
 
 0.740
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
   0.725
nifJ_3
Pyruvate-flavodoxin oxidoreductase.
  
   0.725
OPJ60794.1
Ankyrin repeat protein.
    
 0.675
OPJ56553.1
Ankyrin repeat protein.
    
 0.675
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
Server load: low (20%) [HD]