node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OEI80311.1 | OEI80313.1 | AST99_09840 | AST99_09850 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
OEI80311.1 | OEI80664.1 | AST99_09840 | AST99_07560 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
OEI80311.1 | OEI80672.1 | AST99_09840 | AST99_07605 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
OEI80311.1 | OEI80673.1 | AST99_09840 | AST99_07610 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.843 |
OEI80311.1 | OEI80763.1 | AST99_09840 | AST99_07555 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
OEI80311.1 | asd | AST99_09840 | AST99_03080 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.997 |
OEI80311.1 | ilvA | AST99_09840 | AST99_08800 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.914 |
OEI80311.1 | metE | AST99_09840 | AST99_09435 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.879 |
OEI80311.1 | metZ | AST99_09840 | AST99_07565 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.879 |
OEI80311.1 | thrB | AST99_09840 | AST99_09845 | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
OEI80313.1 | OEI80311.1 | AST99_09850 | AST99_09840 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
OEI80313.1 | OEI80664.1 | AST99_09850 | AST99_07560 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
OEI80313.1 | asd | AST99_09850 | AST99_03080 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.533 |
OEI80313.1 | ilvA | AST99_09850 | AST99_08800 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.984 |
OEI80313.1 | metE | AST99_09850 | AST99_09435 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.466 |
OEI80313.1 | thrB | AST99_09850 | AST99_09845 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
OEI80664.1 | OEI80311.1 | AST99_07560 | AST99_09840 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
OEI80664.1 | OEI80313.1 | AST99_07560 | AST99_09850 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
OEI80664.1 | OEI80672.1 | AST99_07560 | AST99_07605 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
OEI80664.1 | OEI80673.1 | AST99_07560 | AST99_07610 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.985 |