node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sps_00916 | Sps_00917 | Sps_00916 | Sps_00917 | PFAM: Universal stress protein family. | Transcriptional regulator, Crp/Fnr family; PFAM: Crp-like helix-turn-helix domain; Cyclic nucleotide-binding domain. | 0.709 |
Sps_00916 | Sps_02957 | Sps_00916 | Sps_02957 | PFAM: Universal stress protein family. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.526 |
Sps_00916 | Sps_03566 | Sps_00916 | Sps_03566 | PFAM: Universal stress protein family. | 'PFAM: Protein of unknown function, DUF412'. | 0.661 |
Sps_00916 | Sps_04240 | Sps_00916 | Sps_04240 | PFAM: Universal stress protein family. | Lipoprotein NlpI, contains TPR repeats; May be involved in cell division. | 0.615 |
Sps_00916 | Sps_04329 | Sps_00916 | Sps_04329 | PFAM: Universal stress protein family. | 'PFAM: Protein of unknown function, DUF'. | 0.568 |
Sps_00916 | mdh | Sps_00916 | Sps_02697 | PFAM: Universal stress protein family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.609 |
Sps_00916 | mutH | Sps_00916 | Sps_02451 | PFAM: Universal stress protein family. | DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.529 |
Sps_00916 | rraB | Sps_00916 | Sps_05289 | PFAM: Universal stress protein family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.606 |
Sps_00916 | ttcA | Sps_00916 | Sps_00915 | PFAM: Universal stress protein family. | Putative ATPase of the PP-loop superfamily implicated in cell cycle control; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.591 |
Sps_00916 | yihI | Sps_00916 | Sps_00132 | PFAM: Universal stress protein family. | Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.534 |
Sps_00917 | Sps_00916 | Sps_00917 | Sps_00916 | Transcriptional regulator, Crp/Fnr family; PFAM: Crp-like helix-turn-helix domain; Cyclic nucleotide-binding domain. | PFAM: Universal stress protein family. | 0.709 |
Sps_00917 | ttcA | Sps_00917 | Sps_00915 | Transcriptional regulator, Crp/Fnr family; PFAM: Crp-like helix-turn-helix domain; Cyclic nucleotide-binding domain. | Putative ATPase of the PP-loop superfamily implicated in cell cycle control; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.423 |
Sps_02957 | Sps_00916 | Sps_02957 | Sps_00916 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | PFAM: Universal stress protein family. | 0.526 |
Sps_02957 | Sps_03566 | Sps_02957 | Sps_03566 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 'PFAM: Protein of unknown function, DUF412'. | 0.759 |
Sps_02957 | Sps_04240 | Sps_02957 | Sps_04240 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Lipoprotein NlpI, contains TPR repeats; May be involved in cell division. | 0.750 |
Sps_02957 | Sps_04329 | Sps_02957 | Sps_04329 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 'PFAM: Protein of unknown function, DUF'. | 0.581 |
Sps_02957 | mdh | Sps_02957 | Sps_02697 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.467 |
Sps_02957 | mutH | Sps_02957 | Sps_02451 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.744 |
Sps_02957 | rraB | Sps_02957 | Sps_05289 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.772 |
Sps_02957 | yihI | Sps_02957 | Sps_00132 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.667 |