STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sps_01401PFAM: SPFH domain / Band 7 family. (264 aa)    
Predicted Functional Partners:
Sps_01400
Membrane-bound serine protease (ClpP class); 'PFAM: NfeD-like C-terminal, partner-binding'.
 
  
 0.970
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.907
nuoC
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.725
Sps_01399
Hypothetical protein; PFAM: Aminoacyl-tRNA editing domain.
 
     0.609
Sps_02335
Putative transcriptional regulator; 'PFAM: Uncharacterized ACR, COG1678'; Belongs to the UPF0301 (AlgH) family.
  
    0.472
Sps_03144
Membrane protein implicated in regulation of membrane protease activity; 'PFAM: NfeD-like C-terminal, partner-binding'.
 
  
 0.439
Sps_00220
Polyketide synthase family protein; 'PFAM: Phosphopantetheine attachment site; Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain'.
  
 
 0.431
Sps_04152
PFAM: Acetyltransferase (GNAT) domain.
  
    0.430
Sps_01398
Molecular chaperone; PFAM: Hsp70 protein.
  
 0.424
Sps_00752
Flp pilus assembly protein TadC; 'PFAM: Type II secretion system (T2SS), protein F'.
   
    0.414
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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