node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sps_02125 | Sps_02436 | Sps_02125 | Sps_02436 | Site-2 protease; PFAM: Peptidase family M50; PDZ domain; TIGRFAM: RIP metalloprotease RseP. | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | 0.638 |
Sps_02125 | Sps_03192 | Sps_02125 | Sps_03192 | Site-2 protease; PFAM: Peptidase family M50; PDZ domain; TIGRFAM: RIP metalloprotease RseP. | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | 0.522 |
Sps_02436 | Sps_02125 | Sps_02436 | Sps_02125 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Site-2 protease; PFAM: Peptidase family M50; PDZ domain; TIGRFAM: RIP metalloprotease RseP. | 0.638 |
Sps_02436 | Sps_03192 | Sps_02436 | Sps_03192 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | 0.921 |
Sps_02436 | bamD | Sps_02436 | Sps_04400 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Beta-barrel assembly machine subunit BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.694 |
Sps_02436 | era | Sps_02436 | Sps_02434 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.840 |
Sps_02436 | lepA | Sps_02436 | Sps_02437 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.835 |
Sps_02436 | minE | Sps_02436 | Sps_01287 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.683 |
Sps_02436 | parC | Sps_02436 | Sps_05100 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.731 |
Sps_02436 | rnc | Sps_02436 | Sps_02435 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.914 |
Sps_02436 | rnhB | Sps_02436 | Sps_02118 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.634 |
Sps_02436 | secY | Sps_02436 | Sps_00385 | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.680 |
Sps_03192 | Sps_02125 | Sps_03192 | Sps_02125 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Site-2 protease; PFAM: Peptidase family M50; PDZ domain; TIGRFAM: RIP metalloprotease RseP. | 0.522 |
Sps_03192 | Sps_02436 | Sps_03192 | Sps_02436 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | 'PFAM: Peptidase S24-like; Signal peptidase, peptidase S26'; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | 0.921 |
Sps_03192 | bamD | Sps_03192 | Sps_04400 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Beta-barrel assembly machine subunit BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.617 |
Sps_03192 | lepA | Sps_03192 | Sps_02437 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.701 |
Sps_03192 | minE | Sps_03192 | Sps_01287 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.683 |
Sps_03192 | parC | Sps_03192 | Sps_05100 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.731 |
Sps_03192 | rnc | Sps_03192 | Sps_02435 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.578 |
Sps_03192 | rnhB | Sps_03192 | Sps_02118 | PFAM: Peptidase S24-like; 'TIGRFAM: signal peptidase I, bacterial type'; Belongs to the peptidase S26 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.677 |