Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Sps_03633Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; PFAM: PLD-like domain. (508 aa)    
Predicted Functional Partners:
clsA
Cardiolipin synthetase 2; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
  
 
0.928
Sps_04119
Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
     
 0.921
Sps_03116
Phosphatidylglycerophosphatase; PFAM: PAP2 superfamily.
    
 0.909
Sps_03634
'PFAM: Dual specificity phosphatase, catalytic domain'.
   
   0.665
Sps_03632
Chemotaxis signal transduction protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
   
 0.606
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.464
Sps_03635
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
   
   0.453
Sps_01645
DNA internalization-related competence protein ComEC/Rec2; PFAM: Competence protein; Domain of unknown function (DUF4131); Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
   
 
 0.447
Sps_03244
PFAM: Family of unknown function (DUF500).
 
    0.445
Sps_00220
Polyketide synthase family protein; 'PFAM: Phosphopantetheine attachment site; Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain'.
  
 
 0.425
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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