STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sps_04549PFAM: HD domain; GAF domain. (538 aa)    
Predicted Functional Partners:
Sps_04548
PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain.
 
 
 0.958
Sps_01305
'PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phospho-acceptor) domain; PAS domain; CHASE3 domain; PAS fold'; TIGRFAM: PAS domain S-box.
  
 
 0.890
Sps_04618
'PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS fold'; TIGRFAM: PAS domain S-box.
  
 
 0.876
Sps_04913
'PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain'; TIGRFAM: ammonium transporter.
 
 
 0.870
Sps_04142
Amino acid ABC transporter substrate-binding protein, PAAT family; 'PFAM: Bacterial extracellular solute-binding proteins, family 3'.
 
 
 0.867
Sps_03886
PAS domain S-box; 'PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS domain; Hpt domain; PAS fold'; TIGRFAM: PAS domain S-box.
 
 
 0.838
Sps_03929
'PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; Hpt domain'.
 
 
 0.826
Sps_03685
PAS domain S-box; 'PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS domain; Hpt domain; PAS fold'; TIGRFAM: PAS domain S-box.
  
 
 0.822
Sps_04546
PFAM: Peptidase family M48.
 
     0.799
Sps_05280
Multi-sensor hybrid histidine kinase; 'PFAM: Cache domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS fold'; TIGRFAM: PAS domain S-box.
 
 
 0.773
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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