STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sps_04647PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signalling domain. (675 aa)    
Predicted Functional Partners:
Sps_03762
Chemotaxis protein histidine kinase-like protein; 'PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain'.
 
 0.976
Sps_00249
CheA signal transduction histidine kinase; 'PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain'.
 
 0.975
Sps_01421
PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.964
Sps_03757
PFAM: CheW-like domain.
 
 0.964
Sps_03632
Chemotaxis signal transduction protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.960
Sps_00248
Chemotaxis signal transduction protein; PFAM: CheW-like domain.
 
 0.959
Sps_03807
PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.957
Sps_03500
Chemotaxis signal transduction protein; PFAM: CheW-like domain.
 
 0.940
Sps_03806
MCP methyltransferase, CheR-type; 'PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain'.
 
 0.937
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.936
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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