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hslO protein (Shewanella piezotolerans) - STRING interaction network
"hslO" - 33 kDa chaperonin in Shewanella piezotolerans
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Predicted Interactions
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hslO33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (286 aa)    
Predicted Functional Partners:
swp_0184
annotation not available (132 aa)
   
   
  0.965
hslV
ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (174 aa)
   
   
  0.782
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (376 aa)
     
   
  0.755
hslU
ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (441 aa)
     
   
  0.752
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity (638 aa)
   
   
  0.740
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] (200 aa)
     
   
  0.604
dnaK
Chaperone protein DnaK; Acts as a chaperone (641 aa)
   
   
  0.595
swp_3058
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (303 aa)
         
  0.590
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family (513 aa)
   
        0.563
swp_2844
annotation not available (146 aa)
   
   
  0.558
Your Current Organism:
Shewanella piezotolerans
NCBI taxonomy Id: 225849
Other names: S. piezotolerans WP3, Shewanella piezotolerans, Shewanella piezotolerans WP3, Shewanella piezotolerans str. WP3, Shewanella piezotolerans strain WP3, Shewanella sp. WP3
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