Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HP15_320Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (133 aa)    
Predicted Functional Partners:
HP15_321
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
  
 
 0.996
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 
 0.992
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
  
 
 0.988
HP15_3367
Twin-arginine translocation pathway signal.
     
 0.906
HP15_3719
Short-chain dehydrogenase/reductase SDR.
    
  0.902
HP15_67
Short-chain dehydrogenase/reductase SDR.
    
  0.902
folE
GTP cyclohydrolase 1.
  
  
 0.789
gch1
GTP cyclohydrolase 1.
  
  
 0.789
HP15_1824
Bifunctional protein includes folylpolyglutamate synthase (FPGS) dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
  
  
 0.751
plsY
Predicted membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
  
    0.690
Your Current Organism:
Marinobacter adhaerens
NCBI taxonomy Id: 225937
Other names: M. adhaerens HP15, Marinobacter adhaerens HP15, Marinobacter adhaerens str. HP15, Marinobacter adhaerens strain HP15, marine bacterium HP15
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