Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ANY63512.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)    
Predicted Functional Partners:
ANY63468.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.645
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
      0.642
ANY63159.1
Serine peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
   
 
 0.508
ANY63387.1
2-alkenal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.508
ANY60921.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 3 family.
       0.408
Your Current Organism:
Comamonas aquatica
NCBI taxonomy Id: 225991
Other names: ATCC 11330, Aquaspirillum aquaticum, C. aquatica, CCUG 15845, CCUG 17395, Commamonas terrigena DNA group 2, DSM 9155, LMG 2370, LMG:2370, NBRC 14918
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