node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANY62319.1 | ANY62321.1 | MA05_09735 | MA05_09745 | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.983 |
ANY62319.1 | ANY62322.1 | MA05_09735 | MA05_09750 | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | 0.876 |
ANY62319.1 | ANY62324.1 | MA05_09735 | MA05_09765 | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.763 |
ANY62319.1 | hscA | MA05_09735 | MA05_09760 | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.478 |
ANY62319.1 | hscB | MA05_09735 | MA05_09755 | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.957 |
ANY62319.1 | iscS | MA05_09735 | MA05_09740 | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.998 |
ANY62321.1 | ANY62319.1 | MA05_09745 | MA05_09735 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.983 |
ANY62321.1 | ANY62322.1 | MA05_09745 | MA05_09750 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | 0.997 |
ANY62321.1 | ANY62324.1 | MA05_09745 | MA05_09765 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
ANY62321.1 | ANY63361.1 | MA05_09745 | MA05_16345 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.481 |
ANY62321.1 | hscA | MA05_09745 | MA05_09760 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.985 |
ANY62321.1 | hscB | MA05_09745 | MA05_09755 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.999 |
ANY62321.1 | iscS | MA05_09745 | MA05_09740 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
ANY62322.1 | ANY62319.1 | MA05_09750 | MA05_09735 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S cluster assembly transcriptional regulator IscR; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.876 |
ANY62322.1 | ANY62321.1 | MA05_09750 | MA05_09745 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.997 |
ANY62322.1 | ANY62324.1 | MA05_09750 | MA05_09765 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.961 |
ANY62322.1 | ANY62609.1 | MA05_09750 | MA05_11560 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.619 |
ANY62322.1 | ANY63361.1 | MA05_09750 | MA05_16345 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.830 |
ANY62322.1 | dnaJ | MA05_09750 | MA05_14900 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.655 |
ANY62322.1 | hscA | MA05_09750 | MA05_09760 | Iron-sulfur cluster assembly protein IscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.830 |