STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANY63900.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)    
Predicted Functional Partners:
ANY61843.1
Gamma carbonic anhydrase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.975
ANY63507.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
  0.860
ANY63437.1
isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.713
aceK
Bifunctional isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.665
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.643
ANY63556.1
Sodium-independent anion transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.642
ANY62506.1
Sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.541
ANY63899.1
acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
       0.538
ANY62552.1
Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.529
ANY63438.1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.517
Your Current Organism:
Comamonas aquatica
NCBI taxonomy Id: 225991
Other names: ATCC 11330, Aquaspirillum aquaticum, C. aquatica, CCUG 15845, CCUG 17395, Commamonas terrigena DNA group 2, DSM 9155, LMG 2370, LMG:2370, NBRC 14918
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