node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EF_2158 | der | EF_2158 | EF_1549 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | GTPase, putative; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.638 |
EF_2158 | dnaG | EF_2158 | EF_1521 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.737 |
EF_2158 | dnaX | EF_2158 | EF_2781 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.743 |
EF_2158 | ligA | EF_2158 | EF_0722 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.725 |
EF_2158 | polA | EF_2158 | EF_0878 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.682 |
EF_2158 | sigA | EF_2158 | EF_1522 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | RNA polymerase sigma-43 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.709 |
der | EF_2158 | EF_1549 | EF_2158 | GTPase, putative; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | 0.638 |
der | dnaG | EF_1549 | EF_1521 | GTPase, putative; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.862 |
dnaB | dnaE | EF_0013 | EF_1044 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | 0.701 |
dnaB | dnaG | EF_0013 | EF_1521 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.989 |
dnaB | dnaX | EF_0013 | EF_2781 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.848 |
dnaB | polA | EF_0013 | EF_0878 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.598 |
dnaE | dnaB | EF_1044 | EF_0013 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.701 |
dnaE | dnaG | EF_1044 | EF_1521 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.830 |
dnaE | dnaX | EF_1044 | EF_2781 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.994 |
dnaE | ligA | EF_1044 | EF_0722 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.515 |
dnaE | polA | EF_1044 | EF_0878 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.635 |
dnaE | sigA | EF_1044 | EF_1522 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | RNA polymerase sigma-43 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.480 |
dnaE | trmD | EF_1044 | EF_1899 | DNA polymerase III, alpha subunit; Similar to SP:P33553, GB:Z12295, PID:1122400, PID:41062, PID:847971, PID:1314251, GB:X56932, SP:P40429, and PID:23691; identified by sequence similarity; putative. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.565 |
dnaG | EF_2158 | EF_1521 | EF_2158 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative. | 0.737 |