STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EF_24452-dehydropantoate 2-reductase, putative; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (313 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.918
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.918
EF_0517
2-dehydropantoate 2-reductase, putative; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
 
0.902
EF_1655
2-dehydropantoate 2-reductase, putative; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
 
0.902
EF_0273
Phosphoglycerate mutase family protein; Similar to GP:9663130; identified by sequence similarity; putative.
     
 0.599
EF_2433
Phosphoglycerate mutase family protein; Similar to GB:L01100, GB:L21181, SP:Q05084, PID:1674386, PID:1674388, PID:1675204, PID:292166, and PID:437367; identified by sequence similarity; putative.
     
 0.599
EF_0516
Membrane protein, putative; Similar to GP:5901699; identified by sequence similarity; putative.
 
   
 0.547
EF_2444
acyl-CoA thioester hydrolase; Similar to SP:P49851; identified by sequence similarity; putative.
       0.501
EF_1657
Membrane protein, putative; Similar to GP:5901699, and GP:5901699; identified by sequence similarity; putative.
 
   
 0.498
tlyA
Similar to SP:P05656, GB:X56098, GB:X54010, GB:M97796, SP:Q02363, PID:184552, and PID:471126; identified by sequence similarity; putative.
      
 0.459
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.