STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lytSSensor histidine kinase; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. (589 aa)    
Predicted Functional Partners:
lytT
Response regulator; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
 
 0.999
lrgB
LrgB family protein; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
 
   
 0.920
EF_3194
LrgA family protein; Identified by match to PFAM protein family HMM PF03788.
 
   
 0.880
EF_1336
Response regulator; Similar to GB:X62055, GB:U15537, SP:P29350, PID:1732418, PID:1732419, PID:183916, PID:338080, PID:35782, PID:557899, PID:557900, GB:X70340, GB:K03222, SP:P01135, PID:183080, PID:339538, PID:339546, and PID:37090; identified by sequence similarity; putative.
 
 
 0.871
EF_3198
Lipoprotein, YaeC family; Identified by match to PFAM protein family HMM PF03481.
     
 0.674
fsrA
Response regulator; Similar to GP:2564260, GB:X70340, GB:K03222, SP:P01135, PID:183080, PID:339538, PID:339546, and PID:37090; identified by sequence similarity; putative.
  
 
 0.629
EF_3199
ABC transporter, permease protein; Similar to GP:5805202; identified by sequence similarity; putative.
       0.529
EF_3200
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
       0.529
EF_0417
Conserved hypothetical protein; Similar to GP:2879913, and GP:2664264; identified by sequence similarity; putative.
 
     0.488
EF_0093
Cell wall surface anchor family protein; Identified by match to TIGR protein family HMM TIGR01167.
 
   
 0.442
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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