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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serS-1seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)    
Predicted Functional Partners:
EF_0838
Pyridoxal phosphate-dependent enzyme, putative; Similar to SP:Q98FF1; identified by sequence similarity; putative.
     
 0.912
EF_2976
Pyridoxal phosphate-dependent enzyme, putative; Identified by match to PFAM protein family HMM PF01053.
     
 0.912
serS-2
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
  
0.901
sdhA-1
L-serine dehydratase, iron-sulfur-dependent, alpha subunit; Identified by match to PFAM protein family HMM PF03313; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.847
sdhB-1
L-serine dehydratase, iron-sulfur-dependent, beta subunit; Identified by match to TIGR protein family HMM TIGR01830; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.817
cysS
cysteinyl-tRNA synthetase; Similar to GB:M82962, SP:Q16819, and PID:535475; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.775
EF_0097
Regulatory protein pfoR, putative; Similar to GB:X75450, GB:X84707, SP:Q16674, PID:438058, PID:683460, GB:X75450, GB:X84707, SP:Q16674, PID:438058, and PID:683460; identified by sequence similarity; putative.
     
 0.713
lysS
lysyl-tRNA synthetase; Similar to GB:Z21958, GB:M25668, GB:L12563, GB:U01828, SP:P11137, GB:U32995, GB:U34059, GB:U34061, GB:U34064, GB:U34065, GB:U34069, GB:U34060, GB:U34062, GB:U34063, GB:U34066, PID:1850617, PID:187381, and PID:409875; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.673
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
 
 0.670
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
  
 0.644
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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