STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EF_0366Conserved hypothetical protein; Similar to GP:10176078, and GP:16415027; identified by sequence similarity; putative. (277 aa)    
Predicted Functional Partners:
EF_0367
Conserved hypothetical protein; Similar to GP:9246918; identified by sequence similarity; putative.
       0.858
EF_0365
Conserved hypothetical protein; Similar to GP:4704640; identified by sequence similarity; putative.
       0.816
EF_1163
L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.
       0.581
EF_1186
Identified by match to TIGR protein family HMM TIGR01390; Belongs to the 5'-nucleotidase family.
  
    0.502
EF_1544
Conserved hypothetical protein; Similar to GP:10174223; identified by sequence similarity; putative.
  
     0.475
mprF
Membrane protein, putative; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
    0.472
EF_0946
Conserved hypothetical protein; Similar to SP:P31861, and SP:P31861; identified by sequence similarity; putative.
  
     0.466
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.