STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltFPTS system, mannitol-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (145 aa)    
Predicted Functional Partners:
EF_0406
PTS system, IIBC component; Similar to GP:9622944; identified by sequence similarity; putative.
 
 0.999
EF_0411
PTS system, mannitol-specfic IIBC components; Similar to GP:9622944; identified by sequence similarity; putative.
 
 0.999
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Similar to PIR:C39435; identified by sequence similarity; putative; Belongs to the mannitol dehydrogenase family.
 
 0.999
EF_0407
Transcriptional regulator, putative; Similar to SP:P10250, and PID:44228; identified by sequence similarity; putative.
 
  
 0.970
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
 0.968
EF_0717
PTS system, fructose-specific family, IIABC components; Identified by match to PFAM protein family HMM PF02653.
 
  
 0.950
EF_0694
PTS system, fructose-specific family, IIBC components; Similar to GP:10173443; identified by sequence similarity; putative.
 
  
 0.944
EF_0408
PTS system, IIA component; Similar to GB:X02596, GB:U07000, GB:X14676, GB:X14677, GB:M17542, GB:M24603, SP:P11274, PID:487345, PID:487346, PID:487347, PID:930044, GB:X06820, SP:P01121, PID:337393, and PID:36032; identified by sequence similarity; putative.
 
  
 
0.913
ptsI
Phosphoenolpyruvate-protein phosphotransferase enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
    
 0.760
fruK-2
1-phosphofructokinase; Similar to SP:P27369, PID:154510, SP:P27369, and PID:154510; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.730
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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