Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EF_0902Phosphomevalonate kinase; Identified by match to TIGR protein family HMM TIGR00549. (368 aa)    
Predicted Functional Partners:
mvaD
Mevalonate diphosphate decarboxylase; Similar to GP:9937387, and GP:9937387; identified by sequence similarity; putative.
 
 0.999
mvk
Mevalonate kinase; Similar to GP:9937386; identified by sequence similarity; putative.
 
  
 0.998
fni
Isopentenyl diphosphate delta isomerase, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.994
EF_1363
hydroxymethylglutaryl-CoA synthase; Similar to GP:9937383; identified by sequence similarity; putative.
 
  
 0.915
EF_1123
Conserved hypothetical protein; Similar to GP:10175688; identified by sequence similarity; putative.
   
  
 0.853
EF_1364
acetyl-CoA acetyltransferase/hydroxymethylglutaryl-CoA reductase, degradative; Similar to GP:9937384, SP:P17161, GB:X03147, and PID:43926; identified by sequence similarity; putative.
  
 
 0.561
pheT
phenylalanyl-tRNA synthetase, beta subunit; Similar to GB:J04809, SP:P00568, and PID:178322; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.556
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
      
 0.509
EF_0905
Pentapeptide repeat family protein; Similar to GP:10176481; identified by sequence similarity; putative.
       0.462
EF_0906
Conserved hypothetical protein; Similar to GP:6968025; identified by sequence similarity; putative.
       0.442
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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