STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argR-4Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. (149 aa)    
Predicted Functional Partners:
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.919
tlyA
Similar to SP:P05656, GB:X56098, GB:X54010, GB:M97796, SP:Q02363, PID:184552, and PID:471126; identified by sequence similarity; putative.
  
    0.826
ispA
Geranyltranstransferase; Similar to SP:Q08291, GB:U04815, GB:U04818, GB:U04824, GB:U04816, GB:U04817, SP:P21127, PID:189481, PID:507158, PID:507160, PID:507162, PID:507164, PID:507166, PID:507168, PID:507427, and PID:507429; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family.
     
 0.804
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.797
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.797
folD
Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.795
birA
BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.730
nusB
N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
    0.717
argF-1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.652
EF_0976
Conserved hypothetical protein; Similar to GB:X59960, GB:X52679, GB:M59916, GB:M59917, GB:X52678, GB:M81780, GB:X63600, SP:P17405, PID:179095, PID:28880, PID:402621, PID:553192, PID:556809, PID:825629, PID:972769, PID:972770, GB:X59960, GB:X52679, GB:M59916, GB:M59917, GB:X52678, GB:M81780, GB:X63600, SP:P17405, PID:179095, PID:28880, PID:402621, PID:553192, PID:556809, PID:825629, PID:972769, and PID:972770; identified by sequence similarity; putative.
 
     0.600
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.