STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhBPyruvate dehydrogenase complex, E1 component, beta subunit; Similar to GP:7107452, and SP:P21882; identified by sequence similarity; putative. (325 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase complex E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
aceF
Pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase; Similar to GP:580909, GB:L23808, SP:P39900, PID:1688260, PID:435970, and PID:882395; identified by sequence similarity; putative.
 
 0.999
lpdA
Pyruvate dehydrogenase complex E3 component, dihydrolipoamide dehydrogenase; Similar to GB:M27375, GB:M27379, PID:1049145, PID:2358062, PID:292752, PID:619777, PID:975606, GB:M90354, SP:Q13890, and PID:179572; identified by sequence similarity; putative.
 
 0.997
bkdA
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit; Similar to GP:5901696, and GP:5901696; identified by sequence similarity; putative.
 0.997
bkdD
Branched-chain alpha-keto acid dehydrogenase, E3 component, dihydrolipoamide dehydrogenase; Similar to GP:5901695, and GP:5901695; identified by sequence similarity; putative.
 
 0.985
bkdC
Branched-chain alpha-keto acid, E2 component, dihydrolipoamide acetyltransferase; Similar to GP:5901698; identified by sequence similarity; putative.
 
 0.973
EF_2158
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative.
  
 0.965
pflB
Formate acetyltransferase; Similar to SP:P09373, GB:X54936, GB:A18411, SP:P49763, PID:35522, and PID:512449; identified by sequence similarity; putative.
   
 
 0.946
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF02629; Belongs to the pyruvate kinase family.
  
 
 0.941
EF_2559
Pyruvate flavodoxin/ferredoxin oxidoreductase family protein; Similar to GP:4972241, GB:L10243, and PID:152631; identified by sequence similarity; putative.
  
 
 0.941
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.