Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pgkPhosphoglycerate kinase; Similar to SP:Q9Z5C4, SP:P13954, GB:Y07536, PID:46552, and PID:46749; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family. (397 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.999
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
gap-2
Glyceraldehyde 3-phosphate dehydrogenases; Similar to GB:M90354, SP:Q13890, and PID:179572; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.999
gap-1
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GP:2624191; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.998
gpm
Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.992
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF02629; Belongs to the pyruvate kinase family.
 
 
 0.966
fba
Fructose-bisphosphate aldolase class-II; Similar to SP:O65944; identified by sequence similarity; putative.
 
 
 0.958
pgi
Glucose-6-phosphate isomerase; Similar to GP:4928281, SP:P80860, and SP:P80860; identified by sequence similarity; putative.
  
 
 0.957
ppdK
Pyruvate phosphate dikinase; Similar to SP:P22983, GB:X78969, and PID:474915; identified by sequence similarity; putative; Belongs to the PEP-utilizing enzyme family.
    
 0.889
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
 
 
 0.883
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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