Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EF_1968Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF02632. (172 aa)    
Predicted Functional Partners:
EF_1967
Conserved hypothetical protein; Similar to GP:10176390; identified by sequence similarity; putative; Belongs to the UPF0340 family.
 
    0.943
EF_1969
Phosphomethylpyrimidine kinase, putative; Similar to GB:Z15008, GB:Z15009, GB:X73902, SP:Q13753, PID:1236323, PID:1280520, PID:34230, PID:34232, and PID:452755; identified by sequence similarity; putative.
     
 0.917
ecfA2
ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 
 0.908
ecfT
Cobalt transport family protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.829
EF_2152
Cobalt transport family protein; Similar to SP:P27000, and PID:48242; identified by sequence similarity; putative.
  
 
 0.799
ecfA1
ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
   
 
 0.707
EF_2768
Conserved hypothetical protein; Similar to SP:P17155, GB:M18165, and PID:154573; identified by sequence similarity; putative.
 
 
 0.702
EF_2769
ABC transporter, ATP-binding protein; Similar to GB:Z35308, SP:P42197, and PID:516323; identified by sequence similarity; putative.
 
 
 0.537
EF_0580
Conserved hypothetical protein; Similar to GB:X64062, SP:Q00637, PID:1335657, PID:409457, GB:X64062, SP:Q00637, PID:1335657, and PID:409457; identified by sequence similarity; putative.
  
 
 0.498
EF_1966
YitT family protein; Identified by match to PFAM protein family HMM PF02588.
       0.483
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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