Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EF_1978DNA-3-methyladenine glycosylase; Identified by match to PFAM protein family HMM PF02245; Belongs to the DNA glycosylase MPG family. (229 aa)    
Predicted Functional Partners:
EF_1977
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.874
EF_1975
Conserved hypothetical protein TIGR00046; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.863
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
       0.863
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.763
EF_1979
ATPase, AAA family; Similar to GP:10173873; identified by sequence similarity; putative.
       0.745
dtd
Conserved hypothetical protein TIGR00256; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the [...]
  
    0.684
EF_0659
Phage SPO1 DNA polymerase-related protein, putative; Identified by match to PFAM protein family HMM PF03167.
 
   
 0.468
EF_0275
Ada regulatory protein, putative; Similar to GB:L07557, GB:X98025, GB:X98027, GB:X98029, GB:X98022, GB:X98024, GB:X98026, GB:X98028, SP:Q05086, PID:178745, GB:L07557, GB:X98025, GB:X98027, GB:X98029, GB:X98022, GB:X98024, GB:X98026, GB:X98028, SP:Q05086, and PID:178745; identified by sequence similarity; putative.
  
  
 0.411
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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