STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EF_2425Phosphoglucomutase/phosphomannomutase family protein; Similar to GP:5929887; identified by sequence similarity; putative. (574 aa)    
Predicted Functional Partners:
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.969
pgi
Glucose-6-phosphate isomerase; Similar to GP:4928281, SP:P80860, and SP:P80860; identified by sequence similarity; putative.
 
 
 0.967
glcK
Glucokinase; Similar to GP:10174042, GB:Y00264, GB:X06989, GB:M24546, GB:M24547, GB:M34862, GB:M34863, GB:M34864, GB:M34865, GB:M34866, GB:M34867, GB:M34868, GB:M34869, GB:M34870, GB:M34871, GB:M34872, GB:M34873, GB:M34874, GB:M34876, GB:M34877, GB:M34878, GB:M34879, GB:M33112, GB:M34875, GB:M15533, GB:M18734, GB:S60721, GB:S61380, GB:S61383, GB:X06981, GB:X06982, GB:M15532, GB:S41242, GB:S41243, GB:S45135, GB:S45136, GB:X13471, GB:X13475, GB:X13466, GB:X13467, GB:X13468, GB:X13469, GB:X13470, GB:X13472, GB:X13473, GB:X13474, GB:X13476, GB:X13477, GB:X13478, GB:X13479, GB:X13487, GB:X1 [...]
 
 
 0.945
galU
UTP-glucose-1-phosphate uridylyltransferase; Similar to GB:U12778, SP:P45954, and PID:531391; identified by sequence similarity; putative.
    
 0.936
rbsK-2
Transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.934
prsA-1
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.930
prsA-2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.930
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.928
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
 0.919
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.919
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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