close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EF_3000Cytosine/purines, uracil, thiamine, allantoin permease family protein; Identified by match to PFAM protein family HMM PF03155. (498 aa)    
Predicted Functional Partners:
allB
Allantoinase, putative; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
 
  
 0.979
EF_2997
Peptidase, M20/M25/M40 family; Identified by match to PFAM protein family HMM PF01546.
 
  
 0.899
EF_2996
Conserved hypothetical protein; Similar to SP:P24130, GB:S77489, PID:216884, SP:P24130, GB:S77489, and PID:216884; identified by sequence similarity; putative.
 
     0.870
EF_2992
Major facilitator family transporter; Identified by match to PFAM protein family HMM PF03209.
 
  
 0.854
EF_2995
Conserved hypothetical protein; Similar to GP:10173371; identified by sequence similarity; putative.
 
   
 0.785
EF_0381
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.704
EF_2580
D-hydantoinase; Similar to SP:Q45515, GB:M27339, and PID:540472; identified by sequence similarity; putative.
 
  
 0.667
allD
Ureidoglycolate dehydrogenase; Similar to SP:P36947, GB:Z25798, PID:397497, GB:AL009126, SP:P36947, GB:Z25798, PID:397497, and GB:AL009126; identified by sequence similarity; putative; Belongs to the LDH2/MDH2 oxidoreductase family.
 
    0.657
EF_2994
Aminotransferase, class V; Identified by match to PFAM protein family HMM PF00266.
 
   
 0.594
EF_2570
Aldehyde oxidoreductase, putative; Similar to GP:10173362, and SP:Q46509; identified by sequence similarity; putative.
  
  
 0.474
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
Server load: medium (50%) [HD]