Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EF_3000Cytosine/purines, uracil, thiamine, allantoin permease family protein; Identified by match to PFAM protein family HMM PF03155. (498 aa)    
Predicted Functional Partners:
allB
Allantoinase, putative; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
 
  
 0.979
EF_2997
Peptidase, M20/M25/M40 family; Identified by match to PFAM protein family HMM PF01546.
 
  
 0.926
EF_2996
Conserved hypothetical protein; Similar to SP:P24130, GB:S77489, PID:216884, SP:P24130, GB:S77489, and PID:216884; identified by sequence similarity; putative.
 
   
 0.869
EF_2992
Major facilitator family transporter; Identified by match to PFAM protein family HMM PF03209.
 
  
 0.832
EF_2995
Conserved hypothetical protein; Similar to GP:10173371; identified by sequence similarity; putative.
 
   
 0.804
EF_0381
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.698
EF_2580
D-hydantoinase; Similar to SP:Q45515, GB:M27339, and PID:540472; identified by sequence similarity; putative.
 
  
 0.698
allD
Ureidoglycolate dehydrogenase; Similar to SP:P36947, GB:Z25798, PID:397497, GB:AL009126, SP:P36947, GB:Z25798, PID:397497, and GB:AL009126; identified by sequence similarity; putative; Belongs to the LDH2/MDH2 oxidoreductase family.
 
    0.670
EF_2994
Aminotransferase, class V; Identified by match to PFAM protein family HMM PF00266.
 
   
 0.590
EF_2570
Aldehyde oxidoreductase, putative; Similar to GP:10173362, and SP:Q46509; identified by sequence similarity; putative.
  
  
 0.500
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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