Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EF_31426-phosphogluconate dehydrogenase family protein; Similar to GP:10175295; identified by sequence similarity; putative. (299 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 0.974
EF_3235
Gluconate kinase, putative; Similar to GB:X02160, GB:L07782, GB:A18657, GB:M29929, GB:M29930, SP:P06213, PID:186468, PID:186472, PID:186474, PID:307070, PID:33973, PID:386830, PID:463119, PID:512462, PID:553512, and PID:553515; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
  
 
 0.968
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
  
 
0.920
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.918
EF_1918
Conserved hypothetical protein; Similar to SP:O86281; identified by sequence similarity; putative.
    
 0.913
rpe
Ribulose-phosphate 3-epimerase; Similar to SP:P29088, and PID:40792; identified by sequence similarity; putative; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.913
uxuA
Mannonate dehydratase, putative; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
    
 0.900
EF_3141
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Similar to SP:P20572, and PID:1181553; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.790
EF_3139
PTS system, IIC component; Identified by match to PFAM protein family HMM PF03609.
       0.765
EF_3140
Alcohol dehydrogenase, iron-containing; Similar to GB:X71413, GB:X77548, GB:L49399, PID:1381110, PID:469146, and PID:557270; identified by sequence similarity; putative.
     
 0.754
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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