Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EF_3209ABC transporter, ATP-binding protein; Similar to SP:P36879; identified by sequence similarity; putative. (311 aa)    
Predicted Functional Partners:
EF_3208
ABC transporter, permease protein; Similar to GB:J05593, GB:S48568, GB:M32304, GB:X54533, SP:P16035, PID:1517893, PID:307195, PID:339707, and PID:37181; identified by sequence similarity; putative.
  
 0.995
EF_3213
PTS system, IID component; Similar to SP:P25156, GB:X59507, and PID:395159; identified by sequence similarity; putative.
     
 0.784
EF_3210
PTS system, IIA component, putative; Similar to GP:5669855, and GP:8895750; identified by sequence similarity; putative.
     
 0.731
EF_1332
Membrane protein, putative; Similar to GB:J05096, GB:M16795, SP:P50993, PID:179165, PID:179239, and PID:553194; identified by sequence similarity; putative.
  
  
 0.544
EF_0172
Sugar-binding transcriptional regulator, LacI family; Similar to GP:4959405; identified by sequence similarity; putative.
      
 0.502
EF_3207
Dihydrouridine synthase family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
     
 0.495
gor
Glutathione reductase; Identified by match to PFAM protein family HMM PF02852.
 
   
 0.481
gshAB
Glutamate--cysteine ligase, putative/amino acid ligase, putative; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
  
   
 0.444
EF_3211
PTS system, IIB component; Similar to GP:6690421; identified by sequence similarity; putative.
     
 0.440
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
   
 
 0.438
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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