Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EF_3263Conserved hypothetical protein; Similar to GP:10172957; identified by sequence similarity; putative. (27 aa)    
Predicted Functional Partners:
EF_3262
Transcriptional regulator, PemK family; Similar to GB:X06451; identified by sequence similarity; putative.
      
 0.793
EF_3261
Transcriptional regulator, AbrB family; Identified by match to PFAM protein family HMM PF04014.
      
 0.600
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.495
EF_3264
Hypothetical protein; Identified by Glimmer2; putative.
       0.484
EF_2872
Conserved hypothetical protein TIGR00253; Similar to GP:10173941; identified by sequence similarity; putative.
      
 0.419
EF_0619
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.415
EF_0621
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.415
EF_2062
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.415
EF_3266
Ham1 family protein, putative; Similar to GB:L16499, GB:X67235, GB:Z21533, SP:Q03014, PID:292405, PID:32069, and PID:32548; identified by sequence similarity; putative.
       0.414
folE
GTP cyclohydrolase I; Similar to GB:X68194, GB:S72481, and PID:32474; identified by sequence similarity; putative.
       0.414
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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