STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EF_3295Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF04138. (229 aa)    
Predicted Functional Partners:
ychF
GTP-binding protein, GTP1/OBG family; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.814
EF_3297
Conserved hypothetical protein; Similar to GP:10176677, and GP:15026832; identified by sequence similarity; putative.
       0.777
EF_2071
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.757
ezrA
Conserved hypothetical protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.742
EF_2373
Conserved hypothetical protein; Similar to GP:10174311; identified by sequence similarity; putative.
  
     0.737
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.736
EF_3298
Chromosome partitioning protein ParB family; Similar to GP:9968460, and GP:9968460; identified by sequence similarity; putative; Belongs to the ParB family.
       0.732
EF_1745
Conserved hypothetical protein; Similar to GP:4321110, and GP:12723517; identified by sequence similarity; putative.
  
     0.730
EF_3294
Membrane protein, putative; Identified by match to TIGR protein family HMM TIGR01770.
       0.710
EF_0032
Membrane protein, putative; Similar to GP:3043878; identified by sequence similarity; putative.
  
     0.707
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.