node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BT_1478 | BT_4257 | BT_1478 | BT_4257 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.929 |
BT_1478 | hisB | BT_1478 | BT_0203 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.933 |
BT_1478 | hisC | BT_1478 | BT_0202 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.917 |
BT_1478 | hisD | BT_1478 | BT_0201 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.934 |
BT_1478 | hisI | BT_1478 | BT_1377 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.584 |
BT_2690 | hisD | BT_2690 | BT_0201 | Histidine ammonia-lyase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.929 |
BT_4257 | BT_1478 | BT_4257 | BT_1478 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.929 |
BT_4257 | hisB | BT_4257 | BT_0203 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.933 |
BT_4257 | hisC | BT_4257 | BT_0202 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.917 |
BT_4257 | hisD | BT_4257 | BT_0201 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.936 |
BT_4257 | hisI | BT_4257 | BT_1377 | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.585 |
hisA | hisB | BT_1379 | BT_0203 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.985 |
hisA | hisC | BT_1379 | BT_0202 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.975 |
hisA | hisD | BT_1379 | BT_0201 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.988 |
hisA | hisF | BT_1379 | BT_1378 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
hisA | hisG | BT_1379 | BT_0200 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.988 |
hisA | hisH | BT_1379 | BT_1380 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
hisA | hisI | BT_1379 | BT_1377 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.999 |
hisB | BT_1478 | BT_0203 | BT_1478 | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.933 |
hisB | BT_4257 | BT_0203 | BT_4257 | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.933 |