Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BT_2114Conserved hypothetical DNA-binding protein. (258 aa)    
Predicted Functional Partners:
BT_2113
Glycosyl hydrolases 38-like protein.
   
  
 0.613
BT_4719
Conserved hypothetical protein.
   
  
 0.613
BT_4720
Putative RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
   
  
 0.613
BT_2115
Hypothetical protein.
  
    0.537
BT_3744
Conserved hypothetical protein.
      
 0.479
BT_4676
Putative periplasmic protein.
      
 0.426
lpxF
Putative membrane-associated phospholipid phosphatase; Probably removes the 4'-phosphate group from lipid A. Removal of this phosphate group confers resistance to cationic antimicrobial peptides (CAMPs), inflammation-associated peptides produced by the human host. This LPS modification helps maintain the stability of this commensal bacterium in gut microbiota.
      
 0.401
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
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