Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BT_2170Conserved hypothetical protein. (144 aa)    
Predicted Functional Partners:
BT_2171
Putative anti-sigma factor; FrrF homolog.
  
    0.861
BT_2173
SusD homolog.
  
    0.779
BT_2172
SusC homolog.
  
    0.734
BT_2169
RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.551
BT_2168
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.543
BT_0474
D-glycero-D-manno-heptose 1-phosphate kinase.
   
  
 0.452
gmhA
Putative phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
      
 0.442
BT_4652
Oligo alginate lyase-like.
   
  
 0.435
BT_4038
SusD homolog.
   
  
 0.433
BT_1927
Conserved hypothetical protein.
   
  
 0.430
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
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