Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BT_3003Toll-Interleukin receptor. (759 aa)    
Predicted Functional Partners:
BT_4755
Putative two-component system sensor histidine kinase, putative heat shock protein.
  
 0.583
BT_3002
Putative transcriptional regulator.
  
  
 0.579
BT_1183
Two-component system sensor histidine kinase/response regulator, hybrid (one component system).
  
 0.446
BT_2339
Conserved hypothetical protein; Src homology-3.
   
 0.435
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.419
htpG
Chaperone protein htpG (heat shock protein htpG); Molecular chaperone. Has ATPase activity.
  
 0.417
BT_3802
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.410
BT_4602
Chaperone protein dnaK; Belongs to the heat shock protein 70 family.
  
 0.408
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.408
BT_1053
RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
   
    0.406
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
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