| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BT_1713 | BT_2747 | BT_1713 | BT_2747 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.452 |
| BT_1713 | BT_3306 | BT_1713 | BT_3306 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | Putative sugar isomerase. | 0.875 |
| BT_1713 | BT_4004 | BT_1713 | BT_4004 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.412 |
| BT_1713 | BT_4205 | BT_1713 | BT_4205 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.421 |
| BT_1713 | BT_4321 | BT_1713 | BT_4321 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.942 |
| BT_1713 | kdsB | BT_1713 | BT_0745 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.589 |
| BT_1713 | lpxD | BT_1713 | BT_4207 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.450 |
| BT_1713 | lpxK | BT_1713 | BT_1880 | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.451 |
| BT_2747 | BT_1713 | BT_2747 | BT_1713 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | 0.452 |
| BT_2747 | BT_3306 | BT_2747 | BT_3306 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Putative sugar isomerase. | 0.802 |
| BT_2747 | BT_4004 | BT_2747 | BT_4004 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.816 |
| BT_2747 | BT_4205 | BT_2747 | BT_4205 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.779 |
| BT_2747 | BT_4321 | BT_2747 | BT_4321 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.825 |
| BT_2747 | kdsB | BT_2747 | BT_0745 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.966 |
| BT_2747 | lpxD | BT_2747 | BT_4207 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.810 |
| BT_2747 | lpxK | BT_2747 | BT_1880 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.994 |
| BT_3305 | BT_3306 | BT_3305 | BT_3306 | Fructokinase. | Putative sugar isomerase. | 0.840 |
| BT_3305 | BT_3307 | BT_3305 | BT_3307 | Fructokinase. | Lysine decarboxylase; Belongs to the LOG family. | 0.832 |
| BT_3306 | BT_1713 | BT_3306 | BT_1713 | Putative sugar isomerase. | Putative acylneuraminate cytidylyltransferase; Involved in the biosynthesis of 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid used in cell-wall polysaccharides. Catalyzes the hydrolysis of 2-keto-3-deoxy-D- glycero-D-galacto-9-phosphonononic acid (KDN-9-P) to yield 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Also able to hydrolyze N- acetylneuraminate-9-phosphate (Neu5NAc-9-P), 2-keto-3-deoxy-D-manno- octulosonate-8-phosphate (KDO-8-P), phosphoenolpyruvate (PEP), gluconate 6-phosphate, tyrosine phosphate ester and glucose-6-P as substrate. | 0.875 |
| BT_3306 | BT_2747 | BT_3306 | BT_2747 | Putative sugar isomerase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.802 |