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query proteins and first shell of interactors
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second shell of interactors
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BT_3333Arylsulfatase A precursor (ASA); Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS) and dermatan sulfate (DS). Catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl- D-galactosamine 6-sulfate units. GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract. (511 aa)    
Predicted Functional Partners:
chuR
Transcriptional regulator; Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract. May catalyze the activation of chondro-6-sulfatase, i.e. the post- translational modification of a specific serine residue into 3- oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S- adenosyl-L-methionine (SAM). Is also able to oxidize a cysteine residue in a synthetic substrat [...]
 
  
 0.612
BT_0455
Sialidase (Neuraminidase).
  
   0.571
BT_1596
Putative sulfatase yidJ; Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS). 2-O-sulfatase active on unsaturated non- reducing end hexuronate units. Has a slight preference for HS-derived structures. GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract.
 
  
0.500
BT_3332
SusC homolog.
  
    0.496
BT_3349
Putative sulfatase yidJ; Endosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS) and dermatan sulfate (DS). Efficiently hydrolyzes sulfate groups from a broad range of substrate size, including disaccharide to high molecular weight CS and DS polymers. Has a strict specificity for the 4-O-sulfate groups of galactosamine. GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract.
 
  
0.487
BT_3350
Putative chondroitinase (chondroitin lyase); Broad-specificity glycosaminoglycan lyase.
  
  
 0.480
BT_3331
SusD homolog.
  
    0.460
BT_4656
N-acetylglucosamine-6-sulfatase precursor; Exosulfatase involved in the degradation of the glycosaminoglycan (GAG) heparan sulfate (HS). Catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units. GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract. Belongs to the sulfatase family.
 
  
0.456
BT_3334
Two-component system sensor histidine kinase/response regulator, hybrid (one-component system).
  
    0.441
BT_0457
Sialic acid-specific 9-O-acetylesterase.
  
  
 0.429
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
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