Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BT_3755Acetyl-coenzyme A synthetase. (551 aa)    
Predicted Functional Partners:
BT_3756
Transcriptional regulator.
  
 0.991
BT_1747
Pyruvate-flavodoxin oxidoreductase.
  
 0.960
BT_2070
Citrate synthase; Belongs to the citrate synthase family.
  
 0.947
BT_0331
Ketoisovalerate oxidoreductase subunit vorB.
 
 
 0.941
BT_0330
Ketoisovalerate oxidoreductase subunit vorA.
 
 
 0.938
BT_2836
2-oxoglutarate synthase subunit korA.
  
 
 0.938
BT_1917
propionyl-CoA carboxylase beta chain.
  
 0.926
BT_2924
acetyl-CoA synthetase.
  
 
 0.926
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.924
BT_1915
Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.924
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
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