Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BT_3774Alpha-mannosidase. (1198 aa)    
Predicted Functional Partners:
BT_4072
Alpha-mannosidase.
  
  
 
0.917
BT_3783
Putative endonuclease/exonuclease/phosphatase family protein.
  
  
 0.553
BT_3292
Beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
  
  
 0.541
BT_2851
Alpha-galactosidase (melibiase).
  
  
 0.539
BT_3131
Alpha-galactosidase (melibiase).
  
  
 0.535
BT_2226
Transcriptional regulator.
  
    0.524
BT_1033
Glycosidase, PH117-related; Involved in the N-glycan catabolism by catalyzing the reversible phosphorolysis of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine (ManGlcNAc) in a sequential mechanism to yield N-acetyl-D-glucosamine (GlcNAc) and alpha-D-mannose 1-phosphate. It can also use beta-1,4-D- mannosyl-N-acetyl-D-glucosamine-N,N-diacetylchitobiose (ManGlcNAc2) and N,N-diacetylchitobiose (GlcNAc2) as substrates. Belongs to the glycosyl hydrolase 130 family.
  
  
 0.508
BT_2631
Glycoside hydrolase family 73.
  
  
 0.484
BT_0370
Galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
  
    0.462
BT_3592
Alpha-galactosidase precursor.
   
  
 0.460
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
Server load: low (12%) [HD]