STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BT_4657Heparinase III protein. (666 aa)    
Predicted Functional Partners:
BT_4655
Conserved hypothetical protein.
 
    0.914
BT_4652
Oligo alginate lyase-like.
 
    0.884
BT_4658
Glucuronyl hydrolase.
  
 
  0.845
BT_4653
Glucose/galactose transporter.
 
    0.776
BT_4659
SusD homolog.
 
    0.707
BT_4656
N-acetylglucosamine-6-sulfatase precursor; Exosulfatase involved in the degradation of the glycosaminoglycan (GAG) heparan sulfate (HS). Catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units. GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract. Belongs to the sulfatase family.
  
    0.689
BT_2159
Putative oxidoreductase.
 
    0.638
hepC
Heparinase III protein, heparitin sulfate lyase; Specifically cleaves heparan sulfate-rich regions of acidic polysaccharides. Does not act on N,O-desulfated glucosamine or N- acetyl-O-sulfated glucosamine linkages. Functions in cleaving metazoan heparan sulfate and providing carbon, nitrogen and sulfate sources for microorganisms; Belongs to the polysaccharide lyase 12 family.
 
  
0.614
BT_2999
Helicase IV.
  
    0.583
BT_4654
ROK family transcriptional repressor, with glucokinase domain.
  
    0.582
Your Current Organism:
Bacteroides thetaiotaomicron
NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.