menD protein (Bacteroides thetaiotaomicron) - STRING interaction network

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menD

2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (555 aa)

Predicted Functional Partners:

BT_4700

0.996

menB

0.982

BT_4703

0.964

BT_4704

0.964

BT_4699

0.909

BT_2014

0.797

BT_3352

0.550

BT_4698

0.530

BT_2127

0.486

BT_2015

0.453

Your Current Organism:

Bacteroides thetaiotaomicron

NCBI taxonomy Id: 226186
Other names: B. thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron str. VPI-5482, Bacteroides thetaiotaomicron strain VPI-5482

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BT_2014	BT_2015	BT_2014	BT_2015	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	Menaquinone biosynthesis protein MenA-like.	0.997
BT_2014	BT_4700	BT_2014	BT_4700	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	Isochorismate synthase entC.	0.642
BT_2014	BT_4703	BT_2014	BT_4703	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	Chloromuconate cycloisomerase.	0.521
BT_2014	BT_4704	BT_2014	BT_4704	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	O-succinylbenzoic acid--CoA ligase.	0.676
BT_2014	menB	BT_2014	BT_4702	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	Dihydroxynapthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).	0.798
BT_2014	menD	BT_2014	BT_4701	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.797
BT_2015	BT_2014	BT_2015	BT_2014	Menaquinone biosynthesis protein MenA-like.	1,4-dihydroxy-2-naphthoate octaprenyltransferase.	0.997
BT_2015	menB	BT_2015	BT_4702	Menaquinone biosynthesis protein MenA-like.	Dihydroxynapthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).	0.528
BT_2015	menD	BT_2015	BT_4701	Menaquinone biosynthesis protein MenA-like.	2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.453
BT_2127	BT_3352	BT_2127	BT_3352	Putative beta-phosphoglucomutase.	Haloacid dehalogenase-like hydrolase.	0.566
BT_2127	BT_4699	BT_2127	BT_4699	Putative beta-phosphoglucomutase.	Putative hydrolase, haloacid dehalogenase-like hydrolase.	0.709
BT_2127	menB	BT_2127	BT_4702	Putative beta-phosphoglucomutase.	Dihydroxynapthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).	0.447
BT_2127	menD	BT_2127	BT_4701	Putative beta-phosphoglucomutase.	2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.486
BT_3352	BT_2127	BT_3352	BT_2127	Haloacid dehalogenase-like hydrolase.	Putative beta-phosphoglucomutase.	0.566
BT_3352	menB	BT_3352	BT_4702	Haloacid dehalogenase-like hydrolase.	Dihydroxynapthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).	0.451
BT_3352	menD	BT_3352	BT_4701	Haloacid dehalogenase-like hydrolase.	2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.550
BT_4698	BT_4699	BT_4698	BT_4699	Conserved hypothetical protein.	Putative hydrolase, haloacid dehalogenase-like hydrolase.	0.587
BT_4698	BT_4700	BT_4698	BT_4700	Conserved hypothetical protein.	Isochorismate synthase entC.	0.567
BT_4698	BT_4703	BT_4698	BT_4703	Conserved hypothetical protein.	Chloromuconate cycloisomerase.	0.532
BT_4698	BT_4704	BT_4698	BT_4704	Conserved hypothetical protein.	O-succinylbenzoic acid--CoA ligase.	0.535

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