STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YLR298CU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (231 aa)    
Predicted Functional Partners:
YLR147C
Small nuclear ribonucleoprotein Sm D3.
   
 0.996
YIL061C
SNP1-like protein.
   
 0.995
YFL017W-A
SMX2-like protein.
   
 0.994
YER029C
SMB1-like protein.
   
 0.992
YPR182W
SMX3-like protein.
   
 0.992
YOR159C
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.992
YGR074W
SMD1-like protein.
   
 0.990
YPL213W
LEA1-like protein.
   
 0.990
YDR235W
PRP42-like protein.
   
 0.989
YIR009W
MSL1-like protein.
   
 0.988
Your Current Organism:
Saccharomyces kudriavzevii
NCBI taxonomy Id: 226230
Other names: S. kudriavzevii IFO 1802, Saccharomyces kudriavzevii IFO 1802
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.