STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIO13475.1Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (249 aa)    
Predicted Functional Partners:
SIO13460.1
Succinate dehydrogenase subunit A.
 
 0.999
SIO13451.1
Succinate dehydrogenase / fumarate reductase cytochrome b subunit.
 
 
 0.993
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.971
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.962
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.961
SIN75788.1
Rieske Fe-S protein.
  
 0.953
SIN81666.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.940
SIN69132.1
4Fe-4S binding domain-containing protein.
   
 
 0.927
SIN68667.1
Fe-S oxidoreductase.
   
 0.902
SIN95961.1
2-oxoglutarate dehydrogenase E1 component.
 
 
 0.901
Your Current Organism:
Algoriphagus halophilus
NCBI taxonomy Id: 226505
Other names: A. halophilus, Algoriphagus halophilus (Yi and Chun 2004) Nedashkovskaya et al. 2004, DSM 15292, Flexibacteraceae bacterium IMSNU 14013, Hongiella halophila, Hongiella halophila Yi and Chun 2004, IMSNU 14013, KCTC 12051, strain JC 2051
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