STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
sbcDExodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (409 aa)    
Predicted Functional Partners:
SIO25251.1
Exonuclease SbcC.
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.996
SIN83012.1
ATP-dependent DNA helicase RecQ.
   
 0.894
SIO13227.1
ATP-dependent DNA helicase RecQ.
   
 0.894
SIN65828.1
Sulfate permease, SulP family.
   
   0.825
SIN75079.1
Sulfate permease, MFS superfamily.
   
   0.825
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.813
SIN71455.1
Adenylate cyclase, class 3.
  
  0.807
SIO03056.1
Serine/threonine protein kinase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.807
SIN73385.1
DNA ligase-1.
   
 0.795
Your Current Organism:
Algoriphagus halophilus
NCBI taxonomy Id: 226505
Other names: A. halophilus, Algoriphagus halophilus (Yi and Chun 2004) Nedashkovskaya et al. 2004, DSM 15292, Flexibacteraceae bacterium IMSNU 14013, Hongiella halophila, Hongiella halophila Yi and Chun 2004, IMSNU 14013, KCTC 12051, strain JC 2051
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